Celiac disease

Celiac disease is the disease of mucosa of small intestine.
It is characterized by small bowel dysfunction after ingestion of gluten in wheat.

Symptoms of Celiac disease are

  • Diarrhea
  • Stunted growth
  • Bloating
  • Anemia
  • Amenorrhea, infertility and impotence

Diagnosis

  • Serological testing
  • IgA anti tissue transglutaminase
  • IgA antiendomysial antibodies
  • Antigliadin antibodies
  • UGI endoscopy and small intestinal biopsy which reveals villous atrophy

Treatment of celiac disease

  • Withdrawal of wheat/oat/barley/rye containing food items from the diet
  • Dietary supplements
  • Steroids may be helpful in severely ill patients with crisis

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