Liver tumors

Tumor of liver can be categorized as tumor arising in the liver (Primary), or tumor which have started in other organs, but now have spread to the liver (Secondary) Because liver receives a lot of blood from other organs, it is a very common site for the metastatic tumors, and secondary liver tumor are more common than tumors arising in liver itself
Primary tumors of liver can be categorized as benign and malignant

Benign tumors of the liver are

  • Hemangioma
  • Fibrous nodular Hyperplasia
  • Hepatic adenoma
  • Biliary cystadenoma
  • Infantile hemangioendothelioma

Malignant primary tumor of liver are

  • Hepatocellular carcinoma (HCC)
  • Cholangiocarcinoma
  • Biliary cystadenocarcinoma
  • Fibrolamellar carcinoma
  • Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver

Risk factors are

  • Cirrhosis
  • Hepatitis B
  • Hepatitis C
  • Hemochromatosis
  • Membranous obstruction of IVC
  • Wilson disease
  • Hepatocellular carcinoma are diagnosed by raised Alfa-fetoprotein in liver, and CT or MRI findings of arterial enhancing lesion with venous washout in the liver

Treatment of HCC depends upon stage of disease and includes

  • Radiofrequency ablation
  • Percutaneous acetic acid injection
  • Transarterial chemoembolization
  • Transarterial Radioembolization
  • Liver transplantation
  • Oral sorafinib

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