Gastric cancer

  • Gastric cancer is the most common malignant tumor of the stomach
  • Risk factors of gastric cancer are
  • H pylori infection with chronic atrophic gastritis/metaplasia/dysplasia
  • Gastric adenoma
  • Smoking
  • Hereditary non polyposis colorectal cancer
  • Juvenile polyposis
  • Peutz jegher’s Syndrome
  • Obesity
  • Cigarette smoking
  • Clinical symptoms
  • Vomiting
  • Hemetemesis
  • Pain abdomen
  • Post prandial fullness
  • Anorexia
  • Weight loss
  • Diagnosis and staging
  • Endoscopy is the investigation of choice for diagnosis of gastric cancer. Findings on endoscopy are gastric ulcer with raised margins, growth in the stomach
  • CECT abdomen is done in every patient for assessment of resectibility
  • PET scan plays a limited role in these patients

Treatment

  • In patients with resectable tumor, surgery is the treatment of choice
  • In patients with advanced disease, chemotherapy can result in palliation of symptoms, prolong the survival and downstage the tumor, so that surgery can be done

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